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Effect of seasonal variation on the acute toxicity of cyclophosphamide in the Chinese hamster (Cricetulus griseus) and the mouse under laboratory conditions

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The acute toxicity of cyclophosphamide, studied orally in chinese hamsters and intravenously in Tif: MAGf (SPF) mice, showed seasonal variation in Chinese hamsters but not in mice.

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Acknowledgement. I thank Mr R. Gebus for skilful technical and Mr A.P. Grieve for statistical assistance.

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Pericin, C. Effect of seasonal variation on the acute toxicity of cyclophosphamide in the Chinese hamster (Cricetulus griseus) and the mouse under laboratory conditions. Experientia 37, 401–402 (1981). https://doi.org/10.1007/BF01959886

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