European Journal of Pediatrics

, Volume 154, Issue 11, pp 906–908 | Cite as

Serology toBartonella (Rochalimaea) henselae may replace traditional diagnostic criteria for cat-scratch disease

  • David Nadal
  • Reinhard Zbinden
Infectious Diseases Original Paper


Bartonella (Rochalimaea) henselae has been identified as causative agent of cat-scratch disease (CSD). Employing an indirect fluorescence antibody test we found that 20 (100%) out of 20 children with suspected CSD had serum titres toB. henselae of ≥512. By contrast, in all but one of the controls (n=332) including subjects exposed to the same cats, patients with diseases other than CSD, and blood donors the antibody titres were ≤256 (P<0.001). However, significant regional differences in seroprevalence were noted.


Serology toB. henselae may supplant traditional criteria for the diagnosis of CSD and prevent patients from unnecessary surgery.

Key words

Cat-scratch disease Serology Diagnosis 



cat-scratch disease


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Copyright information

© Springer-Verlag 1995

Authors and Affiliations

  • David Nadal
    • 1
  • Reinhard Zbinden
    • 2
  1. 1.Infectious Diseases UnitUniversity Children's HospitalZurichSwitzerland
  2. 2.Department of Medical MicrobiologyUniversity of ZurichZurichSwitzerland

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