Skip to main content
SpringerLink
Log in

Involvement of prolyl endopeptidase in ascidian fertilization

  • Published:
Experientia Aims and scope Submit manuscript

Summary

Inhibitory effects on fertilization of the ascidian of three benzyloxycarbonyl(Z)-aminoacyl prolinals and Z-Gly-Pro-chloromethyl ketone added before and after insemination were examined. The results suggest that the prolyl endopeptidase is involved in the process of fertilization, especially in a process taking place between chorion elevation and cell cleavage.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Hoshi, M., in: Biology of Fertilization, vol. 2, p. 431. Eds C. B. Metz and A. Monroy. Academic Press, Orlando, Fl. 1985.

    Chapter  Google Scholar 

  2. Schuel, H., in: Biology of Fertilization, vol. 3, p. 1. Eds C. B. Metz and A. Monroy. Academic Press, Orlando, Fl. 1985.

    Google Scholar 

  3. Longo, F. J., in: Biology of Fertilization, vol. 3, p. 251. Eds C. B. Metz and A. Monroy. Academic Press, Orlando, Fl. 1985.

    Chapter  Google Scholar 

  4. Yokosawa, H., Miyata, M., Sawada, H., and Ishii, S., J. Biochem.94 (1983) 1067.

    Article  CAS  PubMed  Google Scholar 

  5. Yokosawa, H., Ito, J., Nishikata, M., and Ishii, S., Comp. Biochem. Physiol.86 B (1987) 809.

    Google Scholar 

  6. Yokosawa, H., Nishikata, M., and Ishii, S., J. Biochem.95 (1984) 1819.

    Article  CAS  PubMed  Google Scholar 

  7. Nishikata, M., Yokosawa, H., and Ishii, S., Chem. Pharm. Bull.34 (1986) 2931.

    Article  CAS  Google Scholar 

  8. Sawada, H. Yokosawa, H., Hoshi, M., and Ishii, S., Gamete Res.5 (1982) 291.

    Article  CAS  Google Scholar 

  9. Yoshimoto, T., Orlowski, R. C., and Walter, R., Biochemistry16 (1977) 2942.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Biochemistry, Faculty of Pharmaceutical Sciences, Hokkaido University, 060, Sapporo, Japan

    H. Yokosawa & S. Ishii

  2. Central Research Divison, School of Dentistry, Hokkaido University, 060, Sapporo, Japan

    M. Nishikata

Authors
  1. H. Yokosawa
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M. Nishikata
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. S. Ishii
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Acknowledgment. We are indebted to Dr T. Numakunai of the Marine Biological Station of Tohoku University for collecting the ascidians and to Dr M. Hoshi of the Tokyo Institute of Technology for his helpful discussion. We are also grateful to Dr T. Yoshimoto and Prof. D. Tsuru of Nagasaki University for their generous gift of Z-Gly-Prochloromethyl ketone. This work was supported by a Grant-in-Aid from the Ministry of Education, Science and Culture of Japan.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Yokosawa, H., Nishikata, M. & Ishii, S. Involvement of prolyl endopeptidase in ascidian fertilization. Experientia 45, 381–383 (1989). https://doi.org/10.1007/BF01957486

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01957486

Key words

Search

Navigation