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Chromatin condensation in isolated rat hepatocyte nuclei induced by ribonuclease treatment

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Summary

Ribonuclease treatment of isolated rat hepatocyte nuclei induced a 75% solubilization of hnRNA, a reduction of the qualtity of perichromatin fibrils, and a marked condensation of chromatin.

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Authors and Affiliations

  1. Istituto di Patologia Generale dell'Università, Via S. Giacomo 14, I-40126, Bologna, Italy

    M. Derenzini, Annalisa Pession-Brizzi & F. Novello

Authors
  1. M. Derenzini
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  2. Annalisa Pession-Brizzi
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  3. F. Novello
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Additional information

This investigation was supported by grants from C.N.R. (Roma) and by Pallotti's Legacy for Cancer Research.

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Derenzini, M., Pession-Brizzi, A. & Novello, F. Chromatin condensation in isolated rat hepatocyte nuclei induced by ribonuclease treatment. Experientia 36, 181–183 (1980). https://doi.org/10.1007/BF01953719

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