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Inhibition of nitrosamine formation by ascorbic acid: participation of free radicals in its anaerobic reaction with nitrite

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Summary

The participation of semiquinone free radicals during the reaction of ascorbic acid with acidified sodium nitrite has been demonstrated by ESR spectroscopy unambiguously for the first time. Scavenging of the nitrosating agent, reflected by the observed free radical concentration, unexpectedly occurs with scarcely varying efficiency over the pH range 0.1–4.5.

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Authors and Affiliations

  1. Zentrallaboratorium für Isotopentechnik, Bundesforschungsanstalt für Ernährung, Engesserstrasse 20, D-7500, Karlsruhe 1, Federal Republic of Germany

    W. H. Kalus & W. G. Filby

  2. Institut für Radiochemie, Kernforschungszentrum Karlsruhe, D-7500, Karlsruhe, Federal Republic of Germany

    W. H. Kalus & W. G. Filby

Authors
  1. W. H. Kalus
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  2. W. G. Filby
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Kalus, W.H., Filby, W.G. Inhibition of nitrosamine formation by ascorbic acid: participation of free radicals in its anaerobic reaction with nitrite. Experientia 36, 147–149 (1980). https://doi.org/10.1007/BF01953698

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