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The nucleocytoplasmic distribution of 3-0-methylglucose in the amphibian oocyte

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Summary

Ultra-low temperature microdissection was employed to determine the in situ nucleocytoplasmic distribution 3-0-methylglucose in the amphibian oocyte. The nucleocytoplasmic partition ratio, Kn/c, for this non-metabolizable monosaccharide was 1.54±0.08. The observed asymmetry could be explained by the differential solubility of the solute in the water of the nucleoplasm and the cytoplasm.

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Supported in part by an N.I.H. General Research Support grant to the George Washington University Medical Center.

Acknowledgments. The author wishes to thank Mr T. Poandl for skillful technical assistance.

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Frank, M. The nucleocytoplasmic distribution of 3-0-methylglucose in the amphibian oocyte. Experientia 33, 897–898 (1977). https://doi.org/10.1007/BF01951268

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  • DOI: https://doi.org/10.1007/BF01951268

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