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On induced fragmentation of ovarian oocytes

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Summary

Fragmentation of oocytes was induced in the ovary, via ovulation suppression, by administration of dehydro-epiandrosterone acetate (DHA-Ac) to mature cycling rats. The maximal fragmentation ratio, 15.0±3.2%, was obtained by 10 mg/100 g b.wt/day for 7-day administration of DHA-Ac. The relationship of fragmentation to the first stage of meiosis is also discussed.

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References

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Authors and Affiliations

  1. Department of Anatomy I, School of Medicine, Toyama Medical and Pharmaceutical University, 2630, Sugitani, (Japan 93001)

    H. Shinohara

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  1. H. Shinohara
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Acknowledgments. The author would like to thank Professor T. Matsuda in the Department of Anatomy I for his valuable advices and Proff. E. Nishida and K. Akasofu in the Department of Obstetrics and Gynecology, Kanazawa University, for instructive suggestions and for kindly supplying DHA-Ac.

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Shinohara, H. On induced fragmentation of ovarian oocytes. Experientia 37, 1353–1354 (1981). https://doi.org/10.1007/BF01948407

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  • DOI: https://doi.org/10.1007/BF01948407

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