Summary
The author studied absorption of203Pb after administering intraduodenally203Pb eliminated with bile. The results obtained were compared with absorption of203Pb administered into the duodenum as203PbCl2 in rats forming 2 groups, one with bile ducts cannulated, the other intact. It was found that bile played an important role in absorption of Pb from the gastrointestinal tract. Absorption of Pb203 is significantly reduced if the bile is drained off by means of a canula.
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References
J. C. Aub, L. T. Fairhall, A. S. Minot andP. Reznikoff, inLead Poisoning (Williams and Wilkins Publishers, Baltimore 1926).
K. L. Blaxter andA. T. Cowie, Nature, Lond.157, 588 (1946).
N. Castellino, P. Lamanna andB. Grieco, Folia med.48, 601 (1965).
M. Cikrt, Br. J. ind. Med.29, 74 (1972).
C. D. Klaassen andD. W. Shoeman, Toxic. appl. Pharmac.29, 434 (1974).
M. Cikrt, Arch. Toxic.31, 51 (1973).
M. Cikrt andM. Tichý, Experientia28, 383 (1972).
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Cikrt, M., Tichý, M. Role of bile in intestinal absorption of203Pb in rats. Experientia 31, 1320–1321 (1975). https://doi.org/10.1007/BF01945804
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DOI: https://doi.org/10.1007/BF01945804