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Effect of furosemide on the permeability to Cl of the isolated skin ofLeptodactylus ocellatus

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Summary

Furosemide added to the Ringer solution bathing the external side of the isolated skin ofLeptodactylus ocellatus increased the PD and SCC and inhibited both active chloride influx and passive chloride efflux. The action on chloride permeability is thought to contribute to the diuretic effect of the drug.

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Author notes

  1. C. A. Rabito

    Present address: Centro de Investigaciones Médicas Alberto Einstein, Buenos Aires, Argentina

Authors and Affiliations

  1. Faculty of Medicine of Buenos Aires, Cátedra de Biofísica and Instituto de Investigaciones Cardiológicas, Paraguay, 2155, Buenos Aires, Argentina

    R. Montoreano, C. A. Rabito & M. F. Villamil

Authors
  1. R. Montoreano
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  2. C. A. Rabito
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  3. M. F. Villamil
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Additional information

The authors are greatly indebted to the student fellow Ms.Alda Tufró for her expert collaboration.

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Montoreano, R., Rabito, C.A. & Villamil, M.F. Effect of furosemide on the permeability to Cl of the isolated skin ofLeptodactylus ocellatus. Experientia 31, 1306–1308 (1975). https://doi.org/10.1007/BF01945795

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  • DOI: https://doi.org/10.1007/BF01945795

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