Skip to main content
SpringerLink
Log in

Studies on the effect of allicin (diallyl disulphide-oxide) on alloxan diabetes

  • Specialia
  • Chimica, Biochimica
  • Published:
Experientia Aims and scope Submit manuscript

Summary

On oral administration to alloxan diabetic rabbits, allicin produces an increase in its hypoglycemic action with relation to dose. A short-term treatment with allicin, as well as with tolbutamide, significantly reduced the blood sugar levels and glucose nitrogen ratio of the above animals.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. P. T. Mathew andK. T. Augusti, Indian J. Biochem. Biophys.10, 209 (1973).

    CAS  PubMed  Google Scholar 

  2. H. D. Brahmachari andK. T. Augusti, J. Pharm. Pharmac.14, 617 (1962).

    Article  CAS  Google Scholar 

  3. C. J. Cavallito andJ. H. Bailey, J. Am. chem. Soc.66, 1950 (1944).

    Article  CAS  Google Scholar 

  4. H. D. Brahmachari andK. T. Augusti, J. Pharm. Pharmac.13, 381 (1961).

    Article  CAS  Google Scholar 

  5. A. Asatoor andE. J. King, Biochem. J.56, 44 (1954).

    Article  Google Scholar 

  6. M. Somogyi, J. biol. Chem.195, 19 (1952).

    Article  CAS  Google Scholar 

  7. J. M. Orten andO. W. Neuhaus, inBiochemistry, 8th ed. (The C. V. Mosby Company, Saint Louis 1970), p. 363.

    Google Scholar 

  8. I. D. P. Wootton,Microanalysis in Medical Biochemistry (Churchill. Ltd., London 1964), p. 169 and 173.

    Google Scholar 

  9. R. F. Bradley, Ann. N. Y. Acad. Sci.82, 513 (1959).

    Article  CAS  PubMed  Google Scholar 

  10. G. Unger, L. Freedman andS. L. Shapiro, Proc. Soc. exp. Biol. Med.95, 190 (1957).

    Article  Google Scholar 

  11. K. T. Augusti andP. T. Mathew, Experientia30, 468 (1974).

    Article  CAS  PubMed  Google Scholar 

  12. J. C. Shipp, F. C. Wood jr. andM. Alexander, J. Am. med. Ass.188, 468 (1964).

    Article  CAS  Google Scholar 

  13. K. Prasannan andK. T. Augusti, Indian J. med. Res.61, 1072 (1973).

    CAS  PubMed  Google Scholar 

  14. R. C. Jain, C. R. Vyas andO. P. Mahatma, Lancet2, 1491 (1973).

    Article  CAS  PubMed  Google Scholar 

  15. M. Fujiwara, M. Yoshimura andS. Tsuno, J. Biochem., Tokyo42, 591 (1955).

    Article  CAS  Google Scholar 

  16. A. E. Johnson, H. E. Nursten andA. A. Williams, Chemy. Ind.1, 556 (1971).

    Google Scholar 

  17. T. M. Lukes, J. Food Sci.36, 662 (1971).

    Article  CAS  Google Scholar 

  18. A. Bordia andH. C. Bansal, Lancet2, 1491 (1973).

    Article  CAS  PubMed  Google Scholar 

  19. K. T. Augusti, Paper presented at the annual meeting of the Kerala Chemical Academy, 26th February 1975, Trivandrum, India.

Download references

Author information

Authors and Affiliations

  1. Department of Biochemistry, University of Kerala, Trivandrum, India

    K. T. Augusti

Authors
  1. K. T. Augusti
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Augusti, K.T. Studies on the effect of allicin (diallyl disulphide-oxide) on alloxan diabetes. Experientia 31, 1263–1265 (1975). https://doi.org/10.1007/BF01945769

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01945769

Keywords

Search

Navigation