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Regional distribution of lactate dehydrogenase isoenzymes in adult rat brain

  • Specialia
  • Chimica, Biochimica
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Summary

The highest lactate dehydrogenase (LDH) activity was found in thalamus, statistically significantly less in cerebral and cerebellar cortex and the lowest in pons. LDH1 and LDH4+5 represented 58% and 23% of the total activity in cerebral cortex, 54% and 20% in thalamus, 42% and 4% in cerebellar cortex and 55% and 7% in pons, respectively.

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References

  1. R. V. Živković, B. B. Mršulja andB. M. Djuričić, Experientia31, 404 (1975).

    Article  Google Scholar 

  2. D. M. Dawson, T. L. Goodfriend andN. O. Kaplan, Science143, 929 (1964).

    Article  CAS  PubMed  Google Scholar 

  3. E. M. Tarmy andN. O. Kaplan, J. biol. Chem.243, 2587 (1968).

    Article  CAS  PubMed  Google Scholar 

  4. J. H. Wilkinson,Isoenzymes (E. & F. N. Spon Ltd., London 1965).

    Google Scholar 

  5. H. U. Bergmeyer, E. Bernt andB. Hess, inMethods of Enzymatic Analysis (Ed.H. U. Bergmeyer; Academic Press, New York and London 1963), p. 742.

    Google Scholar 

  6. D. T. Plummer, B. A. Elliot, K. B. Cooke andJ. H. Wilkinson, Biochem. J.87, 416 (1963).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. S. B. Rosalki andJ. H. Wilkinson, Nature, Lond.188, 1110 (1960).

    Article  CAS  PubMed  Google Scholar 

  8. E. F. Hartree, Analyt. Biochem.48, 422 (1972).

    Article  CAS  PubMed  Google Scholar 

  9. P. C. MacDonnel andO. Greengard, Arch. Biochem. Biophys.163, 644 (1974).

    Article  Google Scholar 

  10. J. Nagata, K. Mikushika andY. Tsukada, J. Neurochem.22, 493 (1974).

    Article  CAS  PubMed  Google Scholar 

  11. T. H. Wieland, G. Pfleiderer, J. Haupt andW. Wörner, Biochem. Z.332, 1 (1959).

    PubMed  Google Scholar 

  12. A. Norstrom, G. Eggersten, H. Freden andS. Enestrom, Exp. Neurol.37, 502 (1972).

    Article  CAS  PubMed  Google Scholar 

  13. T. Kato andO. H. Lowry, J. Neurochem.20, 151 (1973).

    Article  CAS  PubMed  Google Scholar 

  14. S. Futterman andJ. H. Kinoshita, J. biol. Chem.234, 3174 (1959).

    Article  CAS  PubMed  Google Scholar 

  15. H. Pasantes-Morales, J. Kletki, P. F. Urban andP. Mandel, J. Neurochem.19, 1183 (1972).

    Article  CAS  PubMed  Google Scholar 

  16. F. C. Kaufman, J. Neurochem.19, 1 (1972).

    Article  Google Scholar 

  17. D. Eby, S. Saltke andA. Lukten, Biochim. biophys. Acta327, 227 (1973).

    Article  CAS  PubMed  Google Scholar 

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Authors wish to express their gratitude toT. C. Detwiler (Downstate Medical Center, New York) for his helpful criticism during preparation of manuscript.

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Živković, R.V., Djuričić, B.M. Regional distribution of lactate dehydrogenase isoenzymes in adult rat brain. Experientia 31, 1258–1260 (1975). https://doi.org/10.1007/BF01945765

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  • DOI: https://doi.org/10.1007/BF01945765

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