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Isoelectric focusing study of radiation damage to dry conalbumin

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Summary

The effect of γ-rays on iron-free conalbumin was studied by isoelectric focusing technique. The results obtained can be interpreted on the basis of radiation-induced conformational changes of the macromolecules through a cleavage of disulphide bridges. Treatments with reagents acting on disulphide bridges lead to isoelectric focusing patterns that confirm this hypothesis.

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Authors and Affiliations

  1. Unità di Biofisica Molecolare CNR-GNCB, Istituto di Fisica dell'Università, I-43100, Parma, (Italy)

    P. Cavatorta, P. R. Crippa & A. M. Tosi

Authors
  1. P. Cavatorta
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  2. P. R. Crippa
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  3. A. M. Tosi
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Additional information

We are indebted to Dr A. Vecli for discussion and criticism of this manuscript. We also wish to acknowledge Dr Baldrati of the Stazione Sperimentale per le Conserve di Parma who kindly performed the irradiations.

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Cavatorta, P., Crippa, P.R. & Tosi, A.M. Isoelectric focusing study of radiation damage to dry conalbumin. Experientia 34, 849–850 (1978). https://doi.org/10.1007/BF01939659

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