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Does pentagastrin suppress secretin induced pepsin secretion in Heidenhain pouch Dogs?

  • Specialia Physiologica
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Summary

Secretin-stimulated pepsin secretion from Heidenhain pouches was significantly depressed by concomitant pentagastrin. Pentagastrin by itself was without effect on pouch pepsin. Methacholine, on the other hand, did not antagonize secretin-stimulated pouch pepsin.

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Author notes

  1. S. Nakajima

    Present address: Department of Internal Medicine, Fujita-Gakuen University, School of Medicine, Toyoake, Aichi, Japan

Authors and Affiliations

  1. Department of Physiology-Pharmacology, Creighton University School of Medicine, 2500 California Street, 68178, Omaha, Nebraska, USA

    D. F. Magee & S. Nakajima

Authors
  1. D. F. Magee
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  2. S. Nakajima
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Additional information

This work was supported by funds from National Science Foundation Grant No. GB-11985 and National Institutes of Health Grant No. AM 17125.

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Magee, D.F., Nakajima, S. Does pentagastrin suppress secretin induced pepsin secretion in Heidenhain pouch Dogs?. Experientia 31, 821–822 (1975). https://doi.org/10.1007/BF01938485

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  • DOI: https://doi.org/10.1007/BF01938485

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