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Erythrophagocytosis by cultured skin fibroblasts from patients with hereditary metabolic disorders

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Abstract

Phagocytosis of native allogenic red blood cells was observed in cultures of skin fibroblasts obtained from patients with neuronal ceroid-lipofuscinosis, Niemann-Pick disease type C and morbus Fabry. Occasional phagocytizing cells were observed in 9 other syndromes. Cells from three normal donors did not phagocytize.

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Authors and Affiliations

  1. 1st Department of Pathology, 1st Prague Medical Faculty, Charles University, Studničkova 2, 128 00, Prague 2

    M. Elleder, E. Holečková & V. Mandys

  2. Institute of Experimental Medicine, Czechoslovak Academy of Sciences, Prague, (Czechoslovakia)

    M. Elleder, E. Holečková & V. Mandys

Authors
  1. M. Elleder
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  2. E. Holečková
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  3. V. Mandys
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Elleder, M., Holečková, E. & Mandys, V. Erythrophagocytosis by cultured skin fibroblasts from patients with hereditary metabolic disorders. Experientia 49, 84–86 (1993). https://doi.org/10.1007/BF01928797

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  • DOI: https://doi.org/10.1007/BF01928797

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