Abstract
Transglutaminase (TGase) activity in the cytosol fraction of the mouse liver increased following intraperitoneal injection of retinoic acid. Retinoic acid inhibited the carbon tetrachloride-induced increase in serum alanine transaminase activity. These findings suggest that TGase is involved in the effect of retinoic acid on carbon tetrachloride-induced liver damage.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Folk, J. E., and Finlayson, J. S., Adv. Prot. Chem.31 (1977) 1.
Folk, J. E., A. Rev. Biochem.49 (1980) 517.
Lorand, L., and Conrad, S. M., Molec. cell. Biochem.58 (1984) 9.
Chung, S. I., Ann. N.Y. Acad. Sci.202 (1972) 240.
Juprelle-Soret, M., Wattiaux-De Coninck, S., and Wattiaux, R., Biochem. J.250 (1988) 421.
Zatloukal, K., Denk, H., Lackinger, E., and Rainer, I., Lab. Invest.61 (1989) 603.
Chytil, F., Pharmac. Rev.36 (1984) 93S.
Piacentini, M., Fesus, L., Sartori, C., and Ceru, M. P., Biochem. J.253 (1988) 33.
Kohno, H., Kashimura, K., Katoh, S., and Ohkubo, Y., Experientia47 (1991) 70.
Omura, T., and Sato, T., J. biol. Chem.239 (1964) 2370.
Bradford, M. M., Analyt. Biochem.72 (1976) 248.
Chiocca, E. A., Davies, P. J. A., and Stein, J. P., J. biol. Chem.263 (1988) 11584.
Schanne, F. A. X., Kane, A. B., Young, E. E., and Farber, J. L., Science206 (1979) 700.
Birckbichler, P. J., and Patterson, M. K. Jr, Ann. N. Y. Acad. Sci.312 (1978) 354.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Kohno, H., Hoshino, Y., Katoh, S. et al. Effect of retinoic acid on liver transglutaminase activity and carbon tetrachloride-induced liver damage in mice. Experientia 48, 386–388 (1992). https://doi.org/10.1007/BF01923436
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF01923436