Summary
Pylorus ligature hides the inhibitory effects of endogenous cholecystokinine-pancreozyme (CCK-PZ) on gastric mucosal secretion and irrigation, whereas the juice collected through transduodenal pyloric fistula makes this phenomenon obvious. It appears that the pyloric fistula encourages inhibition of gastrinic secretion, so that the CCK-PZ can achieve its effects.
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de Saint Blanquat, G., Fritsch, P. & Derache, R. Irrigation et sécrétion gastriques après ligature ou fistule pyloriques chez le rat, sous l'influence d'huile d'olive intra-duodénale. Experientia 31, 1432–1434 (1975). https://doi.org/10.1007/BF01923229
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DOI: https://doi.org/10.1007/BF01923229