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An assessment of the effect of hormone and neurotransmitters on adenine and gluanine derivatives simultaneously in rat brain cortical slices

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Summary

A 2-dimensional thin-layer method has been developed for the separation on cellulose of adenine and guanine derivatives. Using incubated rat cerebral cortex slices it was shown that noradrenaline and acetylcholine stirnulated cAMP and cGMP production respectively but glutamate and γ-aminobutyric acid stimulated production of both cyclic nucleotides.

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References

  1. I. Das and J. S. de Belleroche, in: 10th International Congress of Biochemistry, Hamburg, July 1976, abstracts, p. 457.

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Author notes

  1. I. Das

    Present address: Medical Research Council Toxicology Unit, Clinical Section, St. Bartholomew's Hospital Medical College, Charterhouse Square, EC1M 6BQ, London

Authors and Affiliations

  1. Department of Experimental Pathology, Section of Biochemistry, Cardiothoracic Institute, Brompton, SW3, London

    I. Das & J. S. de Belleroche

  2. Department of Biochemistry, Imperial College of Science and Technology, SW7, London, (England)

    I. Das & J. S. de Belleroche

Authors
  1. I. Das
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  2. J. S. de Belleroche
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Das, I., de Belleroche, J.S. An assessment of the effect of hormone and neurotransmitters on adenine and gluanine derivatives simultaneously in rat brain cortical slices. Experientia 34, 312–313 (1978). https://doi.org/10.1007/BF01923005

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  • DOI: https://doi.org/10.1007/BF01923005

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