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Calcium dependence of rat brain tryptophan hydroxylase

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Summary

The effects of various concentrations of ionized Ca were examined on the activity of rat brain tryptophan hydroxylase previously treated with EGTA. Within the range of ionized Ca-concentrations thought, to be physiologically important (10−8 to 10−5 M), no significant activation of the enzyme occurred, although activation was observed at higher concentrations of the metal.

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Authors and Affiliations

  1. Department of Medical Pharmacology and Therapeutics, California College of Medicine, University of California, 92717, Irvine, California, USA

    R. Weiner & A. S. Fairhurst

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  1. R. Weiner
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  2. A. S. Fairhurst
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Weiner, R., Fairhurst, A.S. Calcium dependence of rat brain tryptophan hydroxylase. Experientia 33, 447–448 (1977). https://doi.org/10.1007/BF01922202

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  • DOI: https://doi.org/10.1007/BF01922202

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