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Effects of increased intracellular Ca2+ on cyclic nucleotides production by liver tissue

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Summary

During hepatointoxication, the increase of intracellular Ca2+ is accompanied by an increase of cAMP. This reversible phenomenon suggests that the production of cAMP is likely to be a response of the cell in order to activate the exclusion of Ca2+.

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Author notes

  1. L. J. Anghileri

    Present address: New England Nuclear Radiopharmaceutical Division, Atomlight Place, 01862, North Billerica, Mass., USA

Authors and Affiliations

  1. Innere Klinik und Poliklinik (Tumorforschung), Klinikum der GHS Essen, Hufelandstrasse 55, D-4300, Essen 1, Germany

    L. J. Anghileri & M. Heidbreder

Authors
  1. L. J. Anghileri
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  2. M. Heidbreder
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Additional information

This work was supported by a grant from the Ministerium für Wissenschaft und Forschung des Landes Nordrhein-Westfalen.

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Anghileri, L.J., Heidbreder, M. Effects of increased intracellular Ca2+ on cyclic nucleotides production by liver tissue. Experientia 33, 415–416 (1977). https://doi.org/10.1007/BF01922183

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