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Serum-growth hormone and free-fatty-acids levels following angiocardiography in children

Wachstumshormon und freie Fettsäuren im Serum nach Angiokardiographie bei Kindern

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Summary

Blood-free-fatty acids (F.F.A.) and growth-hormone levels were determined in 9 children subjected to cardiac catheterization and angiography. A significant rise of growth-hormone level was recorded immediately after angiocardiography, followed by a marked increase of F.F.A. levels 2–4 hours after termination of the catheterization. These results may indicate that the high levels of F.F.A. sustained after cardiac catheterization and angiography are probably due to the increase of growth-hormone secretion during the procedure.

Zusammenfassung

Die Blutspiegel von freien Fettsäuren und Wachstumshormon wurden bei 9 Kindern bestimmt, bei denen eine Herzkatheterisierung und Angiokardiographie durchgeführt wurde. Sofort nach der Angiokardiographie war ein deutlicher Anstieg des Hormonspiegels zu verzeichnen, gefolgt von einem ausgeprägten Anstieg der feien Fettsäuren 2–4 Studen nach Beendigung der Katheterisierung. Diese Ergebnisse sprechen dafür, daß die hohen Fettsäurespiegel nach Herzkatheterisierung und Angiokardiographie wahrscheinlich auf eine gesteigerte Sekretion des Wachstumshormons während des Eingriffs zu beziehen sind.

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References

  1. Oliver, M. F., V. A. Kurien, T. W. Greenwood, Relation between serum-freefatty acids and arrhythmias and death after acute myocardial infarction. Lancet1968/I, 710.

  2. Kurien, V. A., M. F. Oliver, a metabolic cause for arrhythmias during acute myocardial hypoxia. Lancet1970/I, 813.

  3. Soloff, L. A., Arrythmias following infusion of fatty acids. Amer. Heart J.80, 671 (1970).

    Article  PubMed  Google Scholar 

  4. Willebrands, A. F., H. F. Ter Welle, S. J. A. Tasseron: The effect of high molar F.F.A./albumin ratio in the perfusion medium on rhythm and contractility of the isolated rat heart. J. Mol. Cell. Cardiol.5, 259 (1973).

    Article  PubMed  Google Scholar 

  5. Opie, L. H., R. M. Norris, A. J. Holland, P. Owen, A. Thomas, Failure of high blood free fatty acids concentrations to provoke ventricular arrhythmias in experimental coronary artery occlusion. Brit. Heart J.33, 608 (1971).

    Google Scholar 

  6. Opie, L. H., A. Thomas, P. Owen, R. M. Norris, A. J. Holland, S. van Noorden, Failure of high concentrations of circulating free fatty acids to provoke arrhythmias in experimental myocardial infarction. Lancet1971/I, 818.

  7. Raben, M. S., C. H. Hollenberg, Effect of Growth Hormone on plasma fatty acids. J. Clin. Invest.38, 484 (1959).

    PubMed  Google Scholar 

  8. Salter, C. P., D. C. Fluck, L. Stimmler, Effect of open-heart surgery on growth-hormone levels in Man. Lancet1972/II, 853.

  9. Conti, C. R., R. S. Ross, The risks of cardiac catheterization. Amer. Heart J.78, 289 (1969).

    Article  PubMed  Google Scholar 

  10. Herbert, W., K. S. Lau, C. W. Gottlieb, S. J. Bleicher, Coated charcoal immunoassay of insulin. J. Clin. Endocrinology25, 1375 (1965).

    Google Scholar 

  11. Dole, V. P., H. Meinertz, Microdetermination, of long-chain fatty acids in plasma and tissues. J. Biol. Chem.235, 2595 (1960).

    PubMed  Google Scholar 

  12. Greenge, W. A., G. Conron, D. S. Schalch, B. F. Schreiner, Psychologic correlates of growth-hormone and adrenal secretory responses of patients undergoing cardiac catheterization. Psychosom. Med.32, 599 (1970).

    PubMed  Google Scholar 

  13. Bogdonoff, M. D., E. H. Estes, Energy dynamics and acute states of arausal in Man. Psychosom. Med.23, 23 (1961).

    Google Scholar 

  14. Engelberg, H., Heparin lipemia clearing reaction and fat transport in Man. Amer. J. Clin. Nutr.8, 21 (1960).

    PubMed  Google Scholar 

  15. Porte, D. Jr., E. L. Bierman, The effect of heparin infusion on plasma triglyceride in vivo and in vitro with a method for calculating triglyceride turnover. J. Lab. Clin. Med.73, 631 (1969).

    PubMed  Google Scholar 

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  1. A. Simcha

    Present address: Pediatric Department, Hebrew University, Hadassah Medical School, Hadassah University Hospital, P.O. Box 499, Jerusalem, Israel

Authors and Affiliations

  1. Department of Pediatrics and Cardiac Service, Hadassah University Hospital, Jerusalem, Israel

    I. Arad &  A. Simcha

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  1. I. Arad
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  2. A. Simcha
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Arad, I., Simcha, A. Serum-growth hormone and free-fatty-acids levels following angiocardiography in children. Basic Res Cardiol 72, 505–509 (1977). https://doi.org/10.1007/BF01910413

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  • DOI: https://doi.org/10.1007/BF01910413

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