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Different determination of sinoatrial conduction time (SACT) in man

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Summary

Using intracardiac recordings of electrical activity and programmed electrical right atrial stimulation of the human heart, the sinoatrial conduction time (SACT) in the method of Strauß et al. 1973 (SACTc) was calculated in 80 patients with and without disturbances of rhythm and compared to the modified measurement of the SACT in the method reported by Narula et al. in 1978 (SACTN). The number of continuously stimuli varied from 4, 8 and 16 stimuli with a frequency of 10% just above the averaged spontaneous frequency.

The best correlation was found between the SACTc and the SACTN16 (r=0.74; p<0.001) with a regression line of: SACTN16=1.04 SACTc+28.6.

Under these conditions, as opposed to SACTN4 or SACTN8, the most favourable reproducibility and relative coefficient of variation (rVk) could be observed: SACTN16; rVk=9.5%; r=0.91; SACTN8. rVk=12.3%; r=0.89; SACTN4: rVk=24.3%; r=0.53.

Higher individual values for SACTN16 were found by continuous atrial stimulation as compared to other methods of determination indicating mainly a higher depression of sinus node automaticity due to overdrive suppression.

Under parasympathicolysis (1 mg atropine)_the lowest values of SACT were found for SACTN4 (45.9±20.7 ms) coming closest the “true” SACT, since under these conditions neither an increase of the refractory period nor an overdrive suppression exert an influence.

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  1. K. -O. Bischoff

    Present address: Department of Cardiology, University Essen, Hufelandstraße 55, 4300, Essen, FRG

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  1. Department of Cardiology, University Essen, Hufelandstraße 55, 4300, Essen, FRG

    P. Bucher & W. Hager

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  2. P. Bucher
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  3. W. Hager
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Bischoff, K.O., Bucher, P. & Hager, W. Different determination of sinoatrial conduction time (SACT) in man. Basic Res Cardiol 79, 639–648 (1984). https://doi.org/10.1007/BF01908382

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  • DOI: https://doi.org/10.1007/BF01908382

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