Summary
Net transport of inorganic phosphate occurs in the absence of an electrochemical gradient from the mucosal to the serosal bathing solution in the isolated toad urinary bladder. This transport can be inhibited by metabolic inhibitors. The magnitude of this transport can be altered by changes in phosphate concentration or by the addition of parathyroid hormone.
Similar content being viewed by others
References
Agus, Z.S., Puschett, J.B., Senesky, D., Goldberg, M. 1971. Mode of action of parathyroid hormone and cyclic adenosine 3′,5′-monophosphate on phosphate reabsorption in the dog.J. Clin. Invest. 50:617
Bentley, P.J. 1960. The effects of vasopressin on the short-circuit ourrent across the wall of the isolated bladder of the toad,Bufo marinus.J. Endocrinol. 21:161
Butlen, D., Jard, S. 1972. Renal handling of 3′,5′-cyclic AMP in the rat.Pfluegers Arch. 331:172
Goldfarb, S., Agus, Z.S., Goldberg, M. 1974. Tubular sites of action of dibutyryl cyclic AMP on renal phosphate reabsorption. American Society of Nephrology, 7th Annual Meeting, November 1974. p. 33 (Abstr.)
Handler, J., Petersen, M., Orloff, J. 1966. Effect of metabolic inhibitors on the response of the toad bladder to vasopressin.Am. J. Physiol. 211:1175
Hays, R.M., Singer, B., Malamed, S. 1965. The effect of calcium withdrawl on the structure and function of the toad bladder.J. Cell Biol. 25:195
Knox, F.G., Lechene, C. 1974. Effect of parathyroid hormone on distal phosphate reabsorption in the dog. American Society of Nephrology, 7th Annual Meeting, November 1974. p. 46 (Abstr.)
Leaf, A., Anderson, J., Page, L.B. 1958. Active sodium transport by the isolated toad bladder.J. Gen. Physiol. 41:657
Leaf, A., Page, L.B., Peterson, J. 1959. Respiration and active sodium transport of isolated toad bladder.J. Biol. Chem. 234:1625
Mendoza, S.A., Handler, J.S., Orloff, J. 1970. Effect of inhibitors of sodium transport on response of toad bladder to ADH and cyclic AMP.Am. J. Physiol. 219:1440
Murayama, Y., Morel, F., LeGrimellec, C. 1972. Phosphate, calcium and magnesium transfers in proximal tubules and loops of Henle, as measured by single nephron microperfusion experiments in the rat.Pfluegers Arch. 333:1
Peters, J.P., Van Slyke, D.D. 1932. Quantitative Clinical Chemistry,Volume 11, Methods. p. 873. Williams and Wilkins, Baltimore
Staum, B.B., Hamburger, R.J., Goldberg, M. 1972. Tracer microinjection study of renal tubular phosphate reabsorption in the rat.J. Clin. Invest. 51:2271
Ussing, H.H., Zerahn, K. 1951. Active transport of sodium as the source of electric current in the short-circuited frog skin.Acta Physiol. Scand. 23:110
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Sellers, B.B., Hall, J.A., Both, C.W. et al. Active phosphate transport across the urinary bladder of the toad,Bufo marinus . J. Membrain Biol. 32, 291–299 (1977). https://doi.org/10.1007/BF01905223
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1007/BF01905223