Summary
A new method has been suggested for the study of the synthesis of antibodies by isolated cells of immunized animals — indirect hemadsorption reaction. The reaction essentially consists of the fact that erythrocytes sensitized by bacterial haptens become capable of specific attachment to the surface of cells synthesizing antibodies. For sensitivity this test is not inferior to the bacterial attachment reaction and is superior to the latter with regard to specificity, particularly when the object of study is the formation of antibodies to antigens of immotile bacteria.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
Literature Cited
G. Attardi, M. Cohn, K. Horibata et al., Bact. Rev., Vol. 23 (1959), p. 213.
G. Attardi, M. Cohn, K. Horibata et al., J. Immunol., Vol. 92 (1964), p. 372.
M. Kern and H. N. Eisen, J. Exp. Med., Vol. 110 (1959), p. 207.
O. Mäkelä and G. J. V. Nossal, J. Immunol., Vol. 87 (1961), p. 447.
E. Reiss, E. Martens, and W. E. Ehrich, Proc. Soc. Exp. Biol., Vol. 74, New York (1950), p. 732
Author information
Authors and Affiliations
Additional information
Basic principles of the work were reported in July 1964 at the meeting of the immunology section of the 14 Congress of Epidemiologists, Microbiologists, and Specialists in Infectious Diseases.
Rights and permissions
About this article
Cite this article
Shvartsman, Y.S., Ispolatova, A.V. Indirect hemadsorption reaction. Bull Exp Biol Med 61, 599–601 (1966). https://doi.org/10.1007/BF01892466
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF01892466