Skip to main content
SpringerLink
Log in

A search for specific cancer antigens in the organs of cancer patients

  • Oncology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

The method of complement fixation test was used to carry out a comparative serological study of the tissues of malignant tumors and organs in one and the same person. The sera were obtained from rabbits individually to each of the six investigated tumors and to a healthy human spleen. Antitumor and organospecific sera were absorbed by normal formalinized human tissues so as to remove nonspecific antibodies.

It was found that the antigen specific of a malignant tumor in man is contained only in the tissue of the tumor itself and is absent in unaffected organs of the same patients.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Literature Cited

  1. N. D. Anina-Radchenko et al., Vopr. Onkol., No. 11 (1962), p. 3.

    Google Scholar 

  2. V. V. Gorodilova, Byull. Éksper. Biol., No. 6 (1951), p. 460.

    Google Scholar 

  3. V. V. Gorodilova and E. S. Kiseleva, Proc. 2nd All-Union Oncological Conf., Leningrad (1959), p. 87.

  4. L. A. Zil'ber, Uspekhi Sovr. Biol., Vol. 27, No. 2 (1949), p. 185.

    Google Scholar 

  5. V. A. Korenevskaya, Proc.2nd All-Union Oncological Conf., Leningrad (1959), p. 105.

  6. V. S. Korosteleva, In: Problems of Immunology of Normal and Malignant Tissues, Moscow (1956), p. 94.

  7. V. S. Korosteleva and P. N. Kosyakov, Byull. Éksper. Biol., No. 4 (1957), p. 83

    Google Scholar 

  8. V. S. Korosteleva and T. P. Konstantinova,Ibid., No. 9 (1960), p. 101.

    Google Scholar 

  9. P. N. Kosyakov, V. S. Korosteleva, and N. I. Kuznetsova, Byull. Éksper. Biol., No. 9 (1955), p. 63.

    Google Scholar 

  10. P. N. Kosyakov and N. I. Kuznetsova, Byull. Éksper. Biol., No. 6 (1957), p. 49.

    Google Scholar 

  11. P. N. Kosyakov and V. S. Korosteleva, In: Immunological Methods for the Determination of Malignant Growths, Moscow (1959), p. 59.

  12. L. A. Lyudogovskaya, V. S. Tsvetkov, and V. P. Kiryukhin, Vopr. Onkol., No. 3 (1964), p. 18.

    Google Scholar 

  13. Yu. N. Mol'kov, In: Immunological Methods for the Determination of Malignant Growths, Moscow (1959), p. 35.

  14. A. K. Saakov, Antigenic Specificity of Human Cancer Tumors, Thesis, Moscow (1953).

  15. V. Ya. Shevlyagin and I. E. Shustrova, Proc. 2nd All-Union Oncological Conf. Leningrad (1959), p. 82.

  16. L. V. Shershul'skaya, Byull. Éksper. Biol., Vol. 31, No. 6 (1951), p. 455.

    Google Scholar 

  17. D. Burrows, Ann. N. Y. Acad. Sci., Vol. 101, No. 1 (1962), p. 271.

    Google Scholar 

  18. J. G. Makari et al., Brit. Med. J., Vol. 2 (1955), p. 1291.

    Google Scholar 

  19. M. A. Pikovskaya, I. P. Uits, and E. Tanenbaum, Proc. 8th International Cancer Congress, Moscow-Leningrad. Vol. 3 (1963), p. 303.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. The. D. I. Ivanovskii Institute of Biology, Academy of Medical Sciences of the USSR, Moscow

    V. S. Korosteleva & P. N. Kosyakov

Authors
  1. V. S. Korosteleva
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. P. N. Kosyakov
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 61, No. 5, pp. 94–97, May, 1966

Rights and permissions

Reprints and permissions

About this article

Cite this article

Korosteleva, V.S., Kosyakov, P.N. A search for specific cancer antigens in the organs of cancer patients. Bull Exp Biol Med 61, 570–572 (1966). https://doi.org/10.1007/BF01892457

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01892457

Keywords

Search

Navigation