Summary
It was found in a study of the conditions under which Cx-reactive protein forms in the rabbit body after a single injection of various antigens (typhoid vaccine or complete antigen produced from typhoid bacteria after Boivin) that the amount of Cx-reactive protein appearing immediately after antigen injection was correlated with the subsequent value of titers to this antigen. At the same time, the experiments showed that the capacity for production of Cx-reactive protein increases with the advent of age, just as the rabbit's capacity for immunogenesis. All this is evidence in favor of a definite connection existing between the formation of Cx-reactive protein and antibodies.
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Fryazinova, I.B. Principles governing the appearance of Cx-reactive protein and its connection with antibody formation. Bull Exp Biol Med 61, 532–535 (1966). https://doi.org/10.1007/BF01892446
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DOI: https://doi.org/10.1007/BF01892446