Skip to main content
SpringerLink
Log in

Cholinesterase activity of the central nervous system and muscles in the course of experimental tetanus

  • Pathological Physiology and General Pathology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Summary

A study was carried out on the activity of cholinesterase of the gray matter of the spinal cord, rhomboid fossa of the medulla oblongata, spinal ganglia, and muscles of intact rabbits and rabbits in the incubation period, in the stage of local tetanus, and in the stage of general tetanus. Experiments showed a significant decrease of the activity of cholinesterase of the spinal cord and ganglia in the incubation period of the disease. The pathogenetic significance of this phenomenon is discussed in detail.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Literature Cited

  1. I. P. Ashmarin, and A. A. Vorob'eva, Statistical Methods in Microbiologicial Investigations [in Russian], Leningrad (1962).

  2. M. L. Belen'kii, Elements of the Quantitative Evaluation of a Pharmacological Effect [in Russian], Riga (1959).

  3. S. N. Golikov and V. I. Rozengardt, The Pharmacology and Toxicology of Organic Phosphorus Compounds [in Russian], Leningrad (1960).

  4. L. V. Donskaya, Pathophysiological Changes in the Central Nervous System in Experimental Poliomyelitis and Their Significance for the Course of the Disease, Doctorate Dissertation, Leningrad (1962).

  5. G. N. Kryzhanovskii, Byull. Éksper. Biol., No. 11, 38 (1959).

    Google Scholar 

  6. G. N. Kryzhanovskii and A. Kh. Kasymov, Byull. Éksper. Biol., No. 10, 65 (1964).

    Google Scholar 

  7. M. B. Lebedeva and I. L. Chertkov. In book: Problems in Medical Chemistry [in Russian], Vol. 3, Moscow (1951), p. 148.

  8. É. I. Pavlov and V. S. Zueva, Byull. Éksper. Biol., No. 3, 60 (1958).

    Google Scholar 

  9. N. K. Fruentov, Proceedings of the 8th Scientific Conference of Students at the Naval Medical Academy [in Russian], Leningrad (1951), p. 54.

  10. V. B. Brooks, D. R. Curtis, and J. C. Eccles, J. Physiol. Vol. 135, London (1957), p. 655.

    PubMed  Google Scholar 

  11. A. M. Harvey,Ibid, Vol. 96 (1939), p. 348.

    Google Scholar 

  12. S. J. Hestrin, J. Biol. Chem., Vol. 180 (1949), p. 249.

    Google Scholar 

  13. G. Leonardi and M. Bernardi, G. Veneto Sci. Med., Vol. 16 (1961), p. 265.

    PubMed  Google Scholar 

  14. H. Schaefer, Arch. Exp. Path. Pharmacol., Bd 203, S. 54 (1944).

    Google Scholar 

  15. J. Wartenberg, Postery Hig. Med. Dosw., Vol. 14 (1960), p. 615.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Physiology Central Research Laboratory, Leningrad San.-Gig. Medical Institute, Leningrad

    L. V. Donskaya, N. E. Zhebrovskaya & G. N. Tsybulyak

  2. Department of Field Surgery, Order of Lenin Kirov Military Medical Academy, Leningrad

    L. V. Donskaya, N. E. Zhebrovskaya & G. N. Tsybulyak

Authors
  1. L. V. Donskaya
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. N. E. Zhebrovskaya
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. G. N. Tsybulyak
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Donskaya, L.V., Zhebrovskaya, N.E. & Tsybulyak, G.N. Cholinesterase activity of the central nervous system and muscles in the course of experimental tetanus. Bull Exp Biol Med 61, 503–505 (1966). https://doi.org/10.1007/BF01892438

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01892438

Keywords

Search

Navigation