Abstract
The linear dose-response model is considered a conservative, nonthreshold relationship. This is based on a confusion between the sufficient condition (that is, zero slope at zero dose) and the necessary condition (that is, response distinguishable from zero). Once the threshold is properly defined, it is shown that the linear model predicts thresholds for radiation data in good agreement with experimental results.
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Schaeffer, D.J., Janardan, K.G. & Kerster, H.W. Threshold estimation from the linear dose-response model: Method and radiation data. Environmental Management 5, 515–520 (1981). https://doi.org/10.1007/BF01866724
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DOI: https://doi.org/10.1007/BF01866724