Summary
The glia-specific protein S-100 has been demonstrated quantitatively in 1-methyl-1-nitrosourea-induced tumors of the dog CNS and PNS, which is a strong evidence for the neurooncogenic effect of MNU in the dog.
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Stavrou, D., Haglid, K.G. The presence of the S-100 protein in methylnitrosourea induced tumors of the nervous system in dogs. Res. Exp. Med. 164, 59–61 (1974). https://doi.org/10.1007/BF01851965
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DOI: https://doi.org/10.1007/BF01851965