Summary
Human serum inhibition of Ehrlich ascites tumour cell growth and of plant root cell growth depends on the sex, the blood type, and the age of donors, while human states, in health — pregnancy and the early puerperium — and in disease — carcinoma and infection — are also significant.
The aim of this study is to point a remarkably consistent feature: The greater the inhibitory effect of a serum category on Ehrlich cell growth, the lesser the inhibitory effect on plant root growth.
Moreover, the relationships between the observed effects on cell growth of serum from patients with carcinoma and the haematological spectrum in the same patients, point a correlation of growth variation with erythrocyte sedimentation rates and white blood cell counts.
The (patho-)physiological basis of the relationships is not elucidated as yet.
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Abbreviations
- IAA:
-
Indole-3-acetic acid
- SR:
-
Erythrocyte sedimentation rate
- SRa:
-
SR adjusted (see text)
- Hb:
-
Haemoglobin concentration
- E:
-
Ehrlich counts transformed and corrected
- T:
-
Triticum root length increments corrected
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Supported by Statens laegevidenskabelige Forskningsraad, grants No 512-1255 and No 512-2105.
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Hilden, J., Rønnike, F. The toxic effect of human serum on animal and plant cell growth. Res. Exp. Med. 163, 175–183 (1974). https://doi.org/10.1007/BF01851665
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DOI: https://doi.org/10.1007/BF01851665