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Virus-like particles in the cytoplasm of NK/Ly ascites tumour

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Summary

Electron microscopy of untreated ascites tumour revealed that in many cells a juxta-nuclear area was found lying closely adjacent to the eccentrically located nucleus. This area consisted of well developed membranes and vesicles. R.N.P. particles and mitochondria were practically absent in this area. Virus-like particles were found mostly in this area. These particles were morphologically similar to A1- and C-type particles according to the nomenclature ofde Harven.

Zusammenfassung

Bei der elektronenmikroskopischen Untersuchung eines vonNemeth undKellner erzeugten Ascitestumors der Maus war in vielen Zellen ein besonderes juxtanucleäres Areal unmittelbar an dem exzentrisch gelegenen Zellkern nachzuweisen, welches aus stark entwickelten Bläschen und Membranen bestand; es enthielt keine Ribonukleinpartikel und Mitochondrien, dagegen wurden hier virusartige Gebilde gefunden, die dem Typ A1 und C nach der Nomenklatur vonde Harven entsprechen.

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Authors and Affiliations

  1. Pathological Laboratory University of Leiden, Netherlands

    A. P. R. Blok, A. Kurnatowski & J. C. H. de Man

Authors
  1. A. P. R. Blok
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  2. A. Kurnatowski
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  3. J. C. H. de Man
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Additional information

With 3 figures in the test

With technical assistance of Mr.W. Beens.

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Blok, A.P.R., Kurnatowski, A. & de Man, J.C.H. Virus-like particles in the cytoplasm of NK/Ly ascites tumour. Z Krebs-forsch 65, 161–165 (1962). https://doi.org/10.1007/BF01794912

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  • DOI: https://doi.org/10.1007/BF01794912

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