Summary
The action pattern of muscle glycogen synthaseI form was investigated by means of a study of the distribution of radioactive glucosyl units in the glycogen synthesized under variable concentrations of the substrates UDP-glucose and glycogen. A multiple chain mechanism was found to be operative.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Parodi, A. J., Mordoh, J., Krisman, C. R. and Leloir, L. F., Eur. J. Biochem. 16, 499–507 (1970).
Smith, C. H., Villar-Palasi, C., Brown, N. E., Schlender, K. K., Rosenkrans, A. M. and Larner, J., in: Methods in Enzymology Vol. XXVIII Complex Carbohydrates Part B. Ed. by V. Ginsburg. Ac. Press, New York and London, pp. 530–539 (1972).
Thomas, J. A., Schlender, K. K. and Larner, J., Anal. Biochem. 25, 486–499 (1968).
Fales, F. W., Anal. Chem. 31, 1898–1900 (1959).
Salsas, E. and Larner, J., J. Biol. Chem. in press (1975).
Author information
Authors and Affiliations
Additional information
This work was partially supported by U.S. Public Health Service, National Institutes of Health, Grant AM-14334.
A portion of this work was carried out while E. S. was supported by a Fulbright grant awarded by the Comisión de Intercambio Cultural entre España y los Estados Unidos de América. P. Calvo Sotelo, 20, MADRID-1, Spain.
Rights and permissions
About this article
Cite this article
Salsas, E., Larner, J. Action pattern of muscle glycogen synthase. Mol Cell Biochem 7, 195–199 (1975). https://doi.org/10.1007/BF01731409
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF01731409