Abstract
In a sample of cells from a leucocyte culture of an XY/XO mosaic the number of satellite associations between two acrocentric chromosomes (groups 13–15 and 21–22) was determined. Three different types of associations were distinguished. A comparison of the numerical frequencies of the different types in XO and XY cells suggests that the Y chromosome does not take part in the associations and is therefore unsatellited.
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References
De la Chapelle, A. (1961). Constrictions in normal human chromosomes.The Lancet II: 460–462.
Denver Study Group (1960). A proposed standard system of nomenclature of human mitotic chromosomes.The Lancet I: 1063–1065.
Ferguson-Smith, M. A. &S. D. Handmaker (1961). Observations on the satellited human chromosomes.The Lancet I: 638–640.
Hirschhorn, K., W. H. Decker &H. L. Cooper (1960). Human intersex with chromosome mosaicism of type XY/XO.New Eng. J. Med. 263: 1044–1048.
Jacobs, P. A., D. G. Harnden, K. Buckton, W. M. Court Brown, M. King, J. A. McBride, T. N. MacGregor &N. Maclean (1961). Cytogenetic studies in primary amenorrhoea.The Lancet I: 1183–1189.
Lennox, B. (1961). Chromosomes for beginners.The Lancet I: 1046–1051.
Moorhead, P. S., P. C. Nowell, W. J. Mellman, D. M. Battips &D. A. Hungerford (1960). Chromosome preparations of leukocytes cultured from human peripheral blood.Exptl. Cell Res. 20: 613–616.
Ohno, S., J. M. Trujillo, W. D. Kaplan &R. Kinosita (1961). Nucleolus organizers in the causation of chromosomal anomalies in man.The Lancet II: 123–126.
Patau, K. (1960). The identification of individual chromosomes, especially in man.Am. J. Hum. Gen. 12: 250–276.
Patau, K. (1961). Chromosome identification and the Denver report.The Lancet I: 933–934.
Shaw, M. W. (1961). Association of acrocentric chromosomes with the centromere region of chromosome No. 1.The Lancet I: 1351–1352.
Willemse, C., J. M. van Brink &P. L. Los (1962). XY/XO mosaicism.The Lancet I: 488–489.
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van Brink, J.M., Los, P.L. & Nienhaus, A.J. Satellite associations and the identification of the Y chromosome in man. Genetica 33, 45–51 (1963). https://doi.org/10.1007/BF01725746
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DOI: https://doi.org/10.1007/BF01725746