Summary
The technical evolution of ultrasonic equipment provides a high resolution imaging analysis of the vessel wall and thereby offers new possibilities in diagnosing very early atherosclerotic changes. The typical B-mode image in human and animal arteries shows parallel wall contures enclosing a hypoechcic space. In this study in Vitro-and in Vivo-experiments in rabbit aortas document the distance between these contures correlating histologically with a high cholesterol diet caused a broadening of the hypoechoic space in the rabbit aortic vessel wall.
The data demonstrate that high resolution Duplex Sonography is a useful noninvasive approach for the detection of very early atherosclerotic changes in arterial vessel walls in a stage before plaques can be identified.
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Ludwig, M., Kraft, K., Rücker, W. et al. Die Diagnose sehr früher arteriosklerotischer Gefäßwandveränderungen mit Hilfe der Duplexsonographie. Klin Wochenschr 67, 442–446 (1989). https://doi.org/10.1007/BF01725140
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DOI: https://doi.org/10.1007/BF01725140