Abstract
In a study to determine the prevalence of urinary tract infections (UTI) in primary biliary cirrhosis, midstream specimens of urine from 97 females with primary biliary cirrhosis and 85 females with other chronic liver diseases were investigated prospectively for urinary pathogens andMycobacterium gordonae. No significant differences between primary biliary cirrhosis and the two groups were observed in the prevalence of significant bacteriuria (11.3% vs. 7.1%), the prevalence ofEscherichia coli UTI (9.3% vs. 7.1%) or the colony morphology ofEscherichia coli. No mycobacterial species were grown from any sample. In both groups, the prevalence of UTI was higher in patients with cirrhosis (20% in both) than in those without.
Similar content being viewed by others
References
Burroughs AK, Butler P, Sternberg MJE, Baum H: Molecular mimicry in liver disease. Nature 1992, 358: 377–378.
Burroughs AK, Rosenstein IJ, Epstein O, Hamilton Miller JM, Brumfitt W, Sherlock S: Bacteriuria and primary biliary cirrhosis. Gut 1984, 25: 133–137.
Butler P, Valle F, Hamilton Miller JM, Brumfitt W, Baum H, Burroughs AK: M2 mitochondrial antibodies and urinary rough mutant bacteria in patients with primary biliary cirrhosis and in patients with recurrent bacteriuria. Journal of Hepatology 1993, 17: 408–414.
Stemerowicz R, Hopf U, Moller B, Wittenbrink C, Rodloff A, Reinhardt R, Freudenberg M, Galanos C: Are antimitochondrial antibodies in primary biliary cirrhosis induced by R(rough)-mutants of enterobacteriaceae? Lancet 1988, ii: 1166–1170.
Jarikre LN:Mycobacterium gordonae genitourinary disease. Genitourinary Medicine 1992, 68: 45–46.
Vilagut L, Vila J, Vinas O, Pares A, Gines A, Jimenez de Anta MT, Rodes J: Cross-reactivity of anti-Mycobacterium gordonae antibodies with the major mitochondrial autoantigens in primary biliary cirrhosis. Journal of Hepatology 1994, 21: 673–677.
O'Donohue J, McFarlane B, Bomford A, Yates M, Williams R: Antibodies to atypical mycobacteria in primary biliary cirrhosis. Journal of Hepatology 1994, 21: 887–889.
Hopf U, Moller B, Stemerowicz R, Lobeck H, Rodloff A, Freudenberg M, Galanos C, Huhn D: Relation betweenEscherichia coli R (rough)-forms in gut, lipid A in liver, and primary biliary cirrhosis. Lancet 1989, ii: 1419–1422.
Floreani A, Bassendine MF, Mitchison H, Freeman R, James OF: No specific association between primary biliary cirrhosis and bacteriuria? Journal of Hepatology 1989, 8: 201–207.
Kass EH, Miall WE, Stuart KL, Rosner B: Epidemiologic aspects of infections of the urinary tract. In: Kass EH, Brumfitt W (ed): Third International Symposium on Pyelonephritis. University of Chicago Press, Chicago, 1978, p. 1–7.
Sussman M, Asscher AW, Waters WE: Asymptomatic significant bacteriuria in the non-pregnant woman. British Medical Journal 1969, i: 799–803.
Evans DA, Williams DN, Laughlin LW: Bacteriuria in a population-based cohort of women. Journal of Infectious Diseases 1978, 138: 768–773.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
O'Donohue, J., Workman, M.R., Rolando, N. et al. Urinary tract infections in primary biliary cirrhosis and other chronic liver diseases. Eur. J. Clin. Microbiol. Infect. Dis. 16, 743–746 (1997). https://doi.org/10.1007/BF01709256
Issue Date:
DOI: https://doi.org/10.1007/BF01709256