Skip to main content
SpringerLink
Log in

Transsphenoidal microsurgery for selective removal of functional pituitary microadenomas

  • Original Scientific Reports
  • Published:
World Journal of Surgery Aims and scope Submit manuscript

Abstract

The transsphenoidal approach to the pituitary gland is emerging as the safest and most efficacious procedure for the management of pituitary tumors. With the aid of the microscope large tumors producing visual symptoms can be removed and microadenomata producing only signs and symptoms of endocrinopathies can be safely and adequately approached. The procedure is described in this report. The results of its use in 29 patients with selected illustrative case reports are described.

Résumé

L'approche trans-sphénoidale dans la chirurgie de l'hypophyse est en voie de devenir la technique de choix dans le traitement des tumeurs hypophysaires. L'emploi du microscope permet d'exciser non seulement les tumeurs volumineuses responsables de symptÔmes visuels mais aussi les microadénomes manifestés uniquement par des syndrÔmes endocrinologiques et ceci adéquatement et sans risque. L'article décrit la technique et rapporte les résultats obtenus chez 29 patients en plus de présenter en détails quelques cas choisis pour leur représentativité.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Krause, F.: Hirnchirugie (Freilegungder Hypophyse). Dtsch. Klin.8:1004, 1905

    Google Scholar 

  2. Halstead, A.E.: Remarks on the operative treatment of tumors of the hypophysis: Report on two cases operated on by an oronasal method. Surg. Gynecol. Obstet.10:494, 1910

    Google Scholar 

  3. Cushing, H.: Surgical experiences with pituitary disorders. J.A.M.A.63:1515, 1914

    Google Scholar 

  4. Gulot, G.: Adenomes Hypophysaires. Paris, Masson, 1958

    Google Scholar 

  5. Hardy, J., Wigser, S.M.: Trans-sphenoidal surgery of pituitary fossa tumors with televised radiofluoroscopic control. J. Neurosurg.23:612, 1965

    Google Scholar 

  6. Hardy, J., Ciric, I.S.: Selective anterior hypophysectomy in the treatment of diabetic retinopathy: a transsphenoidal microsurgical technique. J.A.M.A.203 (2), 95, 1968

    Google Scholar 

  7. Olson, D.R., Guiot, G., Dermone, P.: The symptomatic empty sella: prevention and correction via the transsphenoidal approach. J. Neurosurg.37:533, 1972

    Google Scholar 

  8. Samaan, N.A., Leavens, M.E., Jesse, R.J., Jr.: Pituitary tumors: recent advances in diagnosis and management. Tex. Med.70:55, 1974

    Google Scholar 

  9. Bohmer, T., Berdal, P., Hangen, H.N.: Transphenoidal subtotal hypophysectomy in the treatment of acromegaly. Acta Endocrinol.77:477, 1974

    Google Scholar 

  10. Ciric, I.S., Tarkington, J.: Transsphenoidal microsurgery. Surg. Neurol.2(3):207, 1974

    Google Scholar 

  11. Dalton, G.: Transsphenoidal hypophysectomy for pituitary tumors. Proc. R. Soc. Med.67:885, 1974

    Google Scholar 

  12. Guiot, G., Thibaut, B.: L'extirpation des adenomes hypophysaires par voie transsphenoidale. Neurochirurgie1:133, 1959

    Google Scholar 

  13. Williams, R.A.: Transsphenoidal hypophysectomy for acromegaly. Proc. Soc. Med.67:881, 1974

    Google Scholar 

  14. Nasr, H., Mozaffarian, G., Pensky, J., Pearson, O.H.: Prolactin secreting pituitary tumors in women. J. Clin. Endocrinol. Metab.35:505, 1972

    Google Scholar 

  15. Pearson, O.H., Brodkey, J.S., Kaufman, B.: Endocrine evaluation and indications for surgery of functional pituitary adenomas. Clin. Neurosurg.21:26, 1974

    Google Scholar 

  16. Forbes, A.P., Henneman, P.H., Griswold, G.C., Albright, F.: Syndrome characterized by galactorrhea, amenorrhea, and low urinary FSH: comparison with acromegaly and normal lactation. J. Clin. Endocrinol. Metab.14:265, 1954

    Google Scholar 

  17. Lawrence, J.H., Tobias, C.A., Linfoot, J.A., Boen, J.L., Chong, C.Y.: Heavy particle therapy in acromegaly and Cushing disease. J.A.M.A.235:2307, 1976

    Google Scholar 

  18. Nelson, D.H., Meakin, J.W., Thorn, G.W.: ACTH producing pituitary tumors following adrenalectomy for Cushing's syndrome. Ann. Intern. Med.52:560, 1960

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Section of Neurosurgery, University of Missouri Medical Center, 65201, Columbia, Missouri, USA

    Karl D. Nielson M.D.,  Clark Watts M.D. & Kemp Clark M.D.

  2. Division of Neurosurgery, Southwestern Medical School, Dallas, Texas, USA

    Karl D. Nielson M.D.,  Clark Watts M.D. & Kemp Clark M.D.

Authors
  1. Karl D. Nielson M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Clark Watts M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Kemp Clark M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Doctor Nielson is sponsored by the U. S. Navy. The opinions expressed are those of the authors and in no way reflect the official view of the Bureau of Medicine and Surgery of the Navy or of the United States Naval service at large.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Nielson, K.D., Watts, C. & Clark, K. Transsphenoidal microsurgery for selective removal of functional pituitary microadenomas. World J. Surg. 1, 79–84 (1977). https://doi.org/10.1007/BF01654738

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01654738

Keywords

Search

Navigation