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Primär beidseitiges, adrenales, hochmalignes B-Zell-Lymphom mit Meningiosis lymphoblastica

Primary B-cell non-hodgkin's lymphoma of both adrenal glands with lymphomatous leptomeningitis: Case report, literature review and therapeutic considerations

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Summary

A 64-year-old man with high malignant B-cell lymphoma in both adrenal glands was investigated. Adrenal insufficiency was his predominant symptom at presentation. Despite surgical resection of the malignancy and cytostatic chemotherapy leptomeningeal involvement occurred and the patient died nine month after the diagnosis. Nine so far reported cases with primary adrenal lymphoma were reviewed. One of these also developed lymphomatous leptomeningitis. Suggestions of a pathogenetic contribution of adrenal lymphoma to leptomeningeal involvement and arising therapeutic consequences in the treatment of primary adrenal lymphoma are discussed.

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Authors and Affiliations

  1. Medizinische Universitätsklinik Bonn, Deutschland

    G. M. Robertz-Vaupel, A. G. Glasmacher & H. A. Vaupel

  2. Institut für Pathologie der Universität Bonn, Deutschland

    J. Vogel

  3. Radiologische Universitätsklinik Bonn, Deutschland

    O. Köster

  4. Medizinische Universitätsklinik Bonn-Kardiologie, Deutschland

    L. Pizzulli

Authors
  1. G. M. Robertz-Vaupel
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  2. A. G. Glasmacher
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  3. J. Vogel
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  4. H. A. Vaupel
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  5. O. Köster
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  6. L. Pizzulli
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Additional information

Herrn Prof. Dr. H.J. Dengler zum 65. Geburtstag gewidmet

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Robertz-Vaupel, G.M., Glasmacher, A.G., Vogel, J. et al. Primär beidseitiges, adrenales, hochmalignes B-Zell-Lymphom mit Meningiosis lymphoblastica. Klin Wochenschr 68, 1076–1081 (1990). https://doi.org/10.1007/BF01649310

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  • DOI: https://doi.org/10.1007/BF01649310

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