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Do antibody-coated bacteria prove bacterial prostatitis?

Antikörper-beladene Bakterien bei bakterieller Prostatitis

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Summary

Using the immunofluorescence technique in 187 patients with bacteriologically proven prostatitis according to the Meares-Stamey test demonstrated a significant amount of antibody-coated bacteria (ACB) in their ejaculates. The ACB test was useful to discriminate between chronic bacterial prostatitis and prostatodynia with a sensitivity of 65% and a specifity of 92%; likewise the ACB test is superior to complement and coeruloplasmin estimation in the ejaculate by radial immunodiffusion usually recommended for the differential diagnosis of inflammatory and psychosomatic diseases of the prostate.

Zusammenfassung

Bei 187 Patienten mit der Verdachtsdiagnose einer Prostatitis wurde der immunofluoreszenzmikroskopische Nachweis von Antikörpern auf Bakterien im Ejakulat, der sogenannte Antibody-Coated-Bacteria (ABC)-Test verglichen mit den Ergebnissen der 4-Gläser-Probe nachMeares undStamey. Der ABC-Test konnte mit einer Sensitivität von 65% und einer Spezifität von 92% zwischen einer chronisch bakteriellen Prostatitis und einer Prostatodynie unterscheiden. Der Nachweis von Komplement und Coeruloplasmin im Ejakulat mit Hilfe der radialen Immundiffusion eignet sich dagegen weniger zur Differentialdiagnostik einer erregerbedingten Prostatitis und einer psychosomatischen Erkrankung der Prostata.

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Riedasch, G., Möhring, K. & Ritz, E. Do antibody-coated bacteria prove bacterial prostatitis?. Infection 19 (Suppl 3), S141–S143 (1991). https://doi.org/10.1007/BF01643684

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  • DOI: https://doi.org/10.1007/BF01643684

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