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Serotypes and antimicrobial susceptibility of Streptococcus pneumoniae in west Germany

Serotypen und Resistenzverhalten von Streptococcus pneumoniae in der Bundesrepublik Deutschland

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Summary

Two-hundred-and-six strains ofStreptococcus pneumoniae were isolated in eight centers in West Germany. The prevalent serotypes were: 19, 3, 6, 7, 23 and 15. Seventy-five percent of the strains tested were antigenically identical to the pneumococcal types included in the 14-valent vaccine Pneumovax®. Susceptibility testing revealed resistance to tetracycline (11% of the isolates), co-trimoxazole (7%) and chloramphenicol (2%). Seven percent of the isolates were relatively resistant to penicillin (MIC 0.1–1.0 mg/l).

Zusammenfassung

In einer multizentrischen Studie wurden insgesamt 206 Stämme vonStreptococcus pneumoniae aus acht Instituten in der Bundesrepublik Deutschland untersucht. Die vorherrschenden Serotypen waren 19, 3, 6, 7, 23 und 15. 75% aller isolierten Stämme besitzen das Antigen, das auch in der 14 Polysaccharid-Antigene umfassenden Vakzine Pneumovax® enthalten ist. Bei der Bestimmung der minimalen Hemmkonzentration zeigten 11% der Isolate Resistenz gegen Tetracyclin, 7% gegen Co-Trimoxazol und 2% gegen Chloramphenicol. 7% der Stämme zeigten eine relative Resistenz gegenüber Penicillin (MHK 0,1–1,0 mg/l).

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Authors and Affiliations

  1. Institut für Medizinische Mikrobiologie und Hygiene der Technischen Universität München, Ismaninger Str. 22, D-800, München 80

    D. Milatović,  K. Machka, W. Heck &  I. Braveny

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  1. D. Milatović
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  2. K. Machka
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  3. W. Heck
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  4. I. Braveny
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Milatović, D., Machka, K., Heck, W. et al. Serotypes and antimicrobial susceptibility of Streptococcus pneumoniae in west Germany. Infection 9, 220–222 (1981). https://doi.org/10.1007/BF01640719

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