Summary
The clinical and histological findings in a 54-year-old patient with enteropathy-associated T-cell lymphoma (EATL) occurring 18 years after renal transplantation are presented. Ten years after adult-onset coeliac disease the patient developed medium to large T-cell non-Hodgkin's lymphoma of the small intestine. Epstein-Barr virus (EBV) genome was detected by polymerase chain reaction in the lymphoma tissue and localized via Epstein-Barr virus RNAs in situ hybridization to some of the tumour cells. This is the first case report of EBV-positive EATL occuring in the setting of immunosuppression.
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This work was supported by a grant from the Swiss National Science Foundation 31-28744.90 to B.B.
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Borisch, B., Hennig, I., Horber, F. et al. Enteropathy-associated T-cell lymphoma in a renal transplant patient with evidence of Epstein-Barr virus involvement. Vichows Archiv A Pathol Anat 421, 443–447 (1992). https://doi.org/10.1007/BF01606918
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DOI: https://doi.org/10.1007/BF01606918