Summary
An automated system was developed for on-line monitoring and control of xylose fermentation by a recombinantEscherichia coli. A 7-L fermenter was interfaced with a personal computer. Control circuits were constructed and a software was developed to estimate the states of the fermentation using an Extended Kalman Filter. The automated system combined with the Extended Kalman Filter provided a satisfactory way to obtain on-line information regarding estimation of fermentation parameters.
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Hilaly, A.K., Karim, M.N. & Linden, J.C. Use of an Extended Kalman Filter and development of an automated system for xylose fermentation by a recombinantEscherichia coli . Journal of Industrial Microbiology 13, 83–89 (1994). https://doi.org/10.1007/BF01584103
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DOI: https://doi.org/10.1007/BF01584103