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The response of various types of epilepsy to dilantin therapy

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Conclusions

  1. 1.

    Sodium diphenyl hydantoinate (dilantin) is an extremely powerful anticonvulsant, more than twice as effective as phenobarbital.

  2. 2.

    With dilantin, convulsions tend to be not only less frequent but less severe and followed by less confusion.

  3. 3.

    The dementia characteristic of epilepsy is not affected by dilantin. Although the chronic epileptic with mental deterioration may have fewer seizures with dilantin, special complications in this type of case may constitute a contraindication.

  4. 4.

    Best results are obtained in cases of grand mal without deterioration.

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Authors and Affiliations

  1. Rockland State Hospital, Orangeburg, N. Y.

    Hiram K. Johnson M. D.

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  1. Hiram K. Johnson M. D.
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Johnson, H.K. The response of various types of epilepsy to dilantin therapy. Psych Quar 14, 612–618 (1940). https://doi.org/10.1007/BF01573142

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