Abstract
Skin and tumor grafting experiments performed on F1 hybrid mice indicate that theH(Tla) histocompatibility system is composed of at least two genetic loci,H(Tla-1) andH(Tla-2), and that one of these loci,H(Tla-1), has at least three alleles. We suggest thatH(Tla-1) andH(Tla-2) be renamedH-31 andH-32, respectively.
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Billingham, R.E. and Medawar, P.B.: The technique of free skin grafting in mammals.J. Exp. Biol. 28:385–402, 1951
Boyse, E.A., Flaherty, L., Stockert, E., and Old, L.I.: Histoincompatibility attributable to genes nearH-2 that are not revealed by hemagglutination or cytotoxicity tests.Transplantation 13:431–432, 1972
Boyse, E.A., Old, L.J., and Luell, S.: Antigenic properties of experimental leukemias. II. Immunological studies in vivo with C57BL/6 radiation-induced leukemias.J. Nat. Cancer Inst. 31:987–995, 1963
Boyse, E.A., Old, L.J., and Stockert, E.: The TL (Thymus leukemia) antigen: A review.In P. Grabar and P.A. Miescher (eds.):Immunopathology: Fourth International Symposium, Monte Carlo, pp. 23–40, Schwabe and Co., Basel/Stuttgart, 1965
Flaherty, L. and Bennett, D.: Histoincompatibilities found between congenic strains which differ at loci determining differentiation antigens.Transplantation 16:505–514, 1973
Flaherty, L. and Wachtel, S.S.: H(Tla) system: Allelism and linkage studies.Transplant. Proc., in press, 1975
Klein, J.: List of congenic lines of mice. I. Lines with differences at alloantigen loci.Transplantation 15:137–153, 1973
Snell, G.D. and Stimpfling, J.H.: Genetics of tissue transplantation.In E.L. Green (ed.):Biology of the Laboratory Mouse, pp. 457–491, McGraw-Hill Book Company, New York, 1966
Widmer, M.B., Schendel, D.J., Bach, F.H., and Boyse, E.A.: TheH(Tla) histoeompatibility locus: A study of in vitro lymphocyte reactivity.Transplant. Proc. 5:1663–1667, 1973
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Flaherty, L., Wachtel, S.S. H(Tla) system: Identification of two new loci,H-31 andH-32, and alleles. Immunogenetics 2, 81–85 (1975). https://doi.org/10.1007/BF01572277
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DOI: https://doi.org/10.1007/BF01572277