Abstract
During alcoholic fermentation ofSaccharomyces cerevisiae, the kinetic analysis of the new growth for raw and supplemented supernatants of culture shows a rapid depletion in essential vitamins (biotin, meso-inositol, nicotinic acid). In spite of these limitations, the cells retain a growth potential (in terms of specific growth rate and multiplication factor) found again in a medium completely depleted in essential factor. In light of these results it must be supposed that an accumulation of intracellular vitamin took place during the early stage of the culture and that the dilution effect was a satisfactory explanation for the growth kinetics. An initial biotin concentration of 3–4 μg/l was sufficient to ensure maximum specific growth rate.
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Winter, J.F., Loret, MO. & Uribelarrea, JL. Inhibition and growth factor deficiencies in alcoholic fermentation bySaccharomyces cerevisiae . Current Microbiology 18, 247–252 (1989). https://doi.org/10.1007/BF01570300
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DOI: https://doi.org/10.1007/BF01570300