Abstract
Cells ofBordetella pertussis grown in a bioreactor under stirring conditions were studied to investigate the effect of shear stress on cellular-bound filamentous haemagglutinin (FHA). FHA attached to the bacterial surface, unlike extracellular FHA, was not affected at the shear levels tested. Moreover, no other cellular immunogen involved in the whole-cell protective activity seemed to be affected by hydromechanical forces.
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Rodriguez, M.E., Hozbor, D.F. & Yantorno, O.M. Effect of hydromechanical stress on cellular antigens ofBordetella pertussis . Journal of Industrial Microbiology 17, 53–55 (1996). https://doi.org/10.1007/BF01570149
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DOI: https://doi.org/10.1007/BF01570149