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A comparison of viable counts and adenine nucleotide analysis to determine the effect of antimicrobial agents on dental plaque

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Abstract

The effects of three antimicrobial agents on smooth surface dental plaque in monkeys were assessed using a plaque index, bacterial viable count, and adenine nucleotide analysis. The effects of the agents were revealed equally well when, viability was assayed by extractable adenosine triphosphate (ATP) or conventional viable cell counts. A persistent effect of one of the agents was revealed by both viable count and extractable ATP. These interpretations were supported by calculations of adenylate energy charge from the adenine nucleotide content of the smooth surface dental plaque samples.

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Authors and Affiliations

  1. Etiology Section of the National Caries Program, National Institutes of Health, Park-5 Building, Room 415, 20205, Bethesda, Maryland, USA

    Stanley A. Robrish, Christopher W. Kemp, Doreen Eberlein & William H. Bowen

  2. Faculty of Odontology, University of Gothenburg, Gothenburg, Sweden

    Claes-Göran Emilson

Authors
  1. Stanley A. Robrish
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  2. Claes-Göran Emilson
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  3. Christopher W. Kemp
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  4. Doreen Eberlein
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  5. William H. Bowen
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Robrish, S.A., Emilson, CG., Kemp, C.W. et al. A comparison of viable counts and adenine nucleotide analysis to determine the effect of antimicrobial agents on dental plaque. Current Microbiology 5, 343–347 (1981). https://doi.org/10.1007/BF01566746

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  • DOI: https://doi.org/10.1007/BF01566746

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