Summary and Conclusions
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1.
The changes in the postabsorptive level of serum potassium of mental patients following a course of insulin hypoglycemic treatment is reported and their possible relation to the results of therapy are indicated.
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2.
The potassium tolerance test of Zwemer and Truszkowski has been carried out in a group of mental patients before and after a course of insulin hypoglycemic treatment, and the significance of the findings is discussed.
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3.
The increased sensitivity of some patients to the intravenous injection of potassium chloride is reported and its significance is considered.
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4.
Further lines of investigation are indicated.
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Harris, M. M., Blalock, J. R., and Horwitz, Wm. A.: Metabolic studies during insulin hypoglycemic therapy of the psychoses. Arch. Neurol. and Psychiat., 40:116, 1938.
Harris, M. M., Blalock, J. R., and Horwitz, Wm. A.: Further metabolic studies regarding the effect of insulin hypoglycemic therapy in mental patients.Psychiat. Quart., 12:489, 1938.
Truszkowski, R., and Zwemer, R. L.: Cortico-adrenal insufficiency and potassium metabolism. Biochem. J., 30:1345, 1936.
Zwemer, R. L., and Truszkowski, R.: The importance of cortico-adrenalin regulation of potassium metabolism. Endocrinology, 21:40, 1937.
Zwemer, R. L.: Electrolyte and sugar determinations as indicators of adrenal influence on normal cell activity. Cold Spring Harbor Symposia on Quantitative Biology, 5:323, 1937.
Schenk, F., and Langecker, H.: Uber Gewebesveranderung der Nebennierenrinde des Kaninchens nach chronischer Insulinzufuhr. Endokrinologie, 16:305, 1935.
Schmidt, H. E.: Beitrage zur Histophysiologie des Insulins. Schweiz. Arch. f. Neurol. and Psychiat. Erganz., bd. 39:109, 1937.
Lewis, N. D. C.: The constitutional factors in dementia præcox. Nervous and Mental Disease Monograph series No. 35. Nervous and Mental Disease Publishing Co., New York and Washington, 1923.
Hoskins, R. G., and Sleeper, F. H.: The organic functions in schizophrenia. Arch. Neurol and Psychiat., 30:123, 1933.
Hoskins, R. G., and Freeman, H.: Some effects of a glycerin extract of suprarenal cortex potent by mouth. Endocrinology, 17:29 and 677, 1933.
Zwemer, R. L., and Truszkowski, R.: Factors affecting human postassium tolerance. Proc. Soc. Exper. Biol. Med., 35:424, 1936.
Breh, F., and Gaebler, O. H.: The determination of potassium in blood serum. J. Biol. Chem., 87:81, 1930.
Semler, R.: Uber die Beinflussung der diabetischen Hyperglykämie durch Kalium. Klin. Wchnschr., 4:697, 1925.
Long, C. N. H.: The influence of the pituitary and adrenal glands upon pancreatic diabetes. Medicine, 16:215, 1937.
Hartman, F. A., Spoor, H. J., and Lewis, L. A.: The sodium factor of the adrenal gland. Science, 89:204, 1939.
Winkler, A. W., Hoff, H. E., and Smith, P. K.: Electrocardiagraphic changes and concentration of potassium in serum following intravenous injection of potassium chloride. Amer. J. Physiol., 124:478, 1938.
Norn, M.: Untersuchungen über das Verhaltens des Kaliums im organismus. Skand. Arch. f. Physiol. 55:211, 1939.
Ingle, D. J., Nilson, H. W., and Kendall, E. C.: The effect of cortin on the concentrations of some constituents of the blood of adrenalectomized rats. Amer. J. Physiol., 118:302, 1937.
Kendall, E. C.: A chemical and physiological investigation of the suprarenal cortex. Cold Spring Harbor Symposia on Quantitative Biol., 5:299, 1937.
Bloom, B.: The use of potassium salts in hay fever. J. Amer. Med. Assn., 111:2281, 1938.
Pudenz, R. H., McIntosh, J. F. and McEachern, D.: The role of potassium in familial periodic paralysis. J. Amer. Med. Assn., 111:2253, 1938.
Allers, W. D., Nilson, H. W., Kendall, E. C.: Studies on adrenalectomized dogs: The toxic action of potassium. Proc. Staff Meet., Mayo Clinic, 11:283, 1936.
Loehner, C. A.: The therapeutic effects of adrenal cortex extract on the psychotic patient. Endocrinology, 23:507, 1938.
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Read at the Interhospital Conference of the New York State Hospitals held at the New York Psychiatric Institute and Hospital, April 19, 1939.
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Harris, M.M., Horwitz, W.A. Metabolic studies of mental patients treated with insulin hypoglycemic shock treatment—III. Psych Quar 13, 429–437 (1939). https://doi.org/10.1007/BF01562846
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DOI: https://doi.org/10.1007/BF01562846