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Die essentiellen Fettsäuren im Plasma von Schwerverletzten unter dem Einfluß der parenteralen Ernährung

Essential fatty acids in plasma of patients with heavy injury under the influence of parenteral nutrition

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Summary

After a heavy injury there are characteristic changes of plasma lipids and lipoproteins. In 7 patients up to 40 days after major injury the fatty acids of cholesteryl esters, phospholipids and triglycerides in plasma under the influence of injury, parenteral nutrition with carbohydrates or fat, and protin-sparing therapy were determined by gas liquid chromatography. These patients' increased requirement for linoleic acid is further increased by up to more than 50 g per day by carbohydrate-rich parenteral nutrition, inhibiting lypolysis of linoleic acid from adipose tissue. Protein-sparing therapy without carbohydrates is not sufficient to cover the patients' increased requirement for linoleic acid. Thus, the early administration of fat emulsions in parenteral nutrition is recommended.

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Authors and Affiliations

  1. Forschergruppe Ernährung, Medizinische Poliklinik der Universität München, Germany

    G. Wolfram & J. Eckart

  2. Abteilung für Anaesthesiologic und operative Intensivmedizin Krankenhauszweckverband Augsburg, Germany

    G. Wolfram & J. Eckart

Authors
  1. G. Wolfram
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  2. J. Eckart
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Additional information

Herrn Prof. Dr. N. Zöllner zum 60. Geburtstag gewidmet

Mit Unterstützung der Deutschen Forschungsgemeinschaft

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Wolfram, G., Eckart, J. Die essentiellen Fettsäuren im Plasma von Schwerverletzten unter dem Einfluß der parenteralen Ernährung. Klin Wochenschr 61, 1181–1189 (1983). https://doi.org/10.1007/BF01537429

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  • DOI: https://doi.org/10.1007/BF01537429

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