Abstract
Linkage was established between a number of genes that map on chromosome 3 by studying the distribution patterns of DNA polymorphisms and protein electrophoretic mobility polymorphisms in recombinant inbred (RI) strains of mice. This analysis resulted in the following suggested gene order between the newly assigned genes and previously mapped genes: γ-fibrinogen(Fgg), Xmmv-22 of mink cell focus-inducing (MCF) virus, Ulb small nuclear RNA gene cluster(Rnu-1b), amylase(Amy-1,2), cadmium resistance (cdm), alcohol dehydrogenase-3(Adh-3), alcohol dehydrogenase-1(Adh-1). In situ hybridization to chromosome spreads confirmed the assignment of the Ulb small nuclear RNA (snRNA) gene cluster and the γ-fibrinogen gene to the center of chromosome 3.
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Blatt, C., Saxe, D., Marzluff, W.F. et al. Mapping and gene order of U1 small nuclear RNA, endogenous viralenv sequence, amylase, and alcohol dehydrogenase-3 on mouse chromosome 3. Somat Cell Mol Genet 14, 133–142 (1988). https://doi.org/10.1007/BF01534398
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DOI: https://doi.org/10.1007/BF01534398