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Zur Sensibilitätstestung maligner menschlicher Tumoren gegenüber Cytostatica. II

Screening of malignant tumours against cytostatic drugs

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Summary

Using a sensibility testing method previously described by the authors (3H-thymidine incorporation, liquid scintillation counting), the sensitivity of 30 human tumours (10 recto-sigmoid carcinomas, 10 gastric carcinomas, 10 carcinomas of the breast) was tested in vitro against Trenimon®, Methotrexat® and Natulan®. The results obtained were evaluated statistically. Each tumour proved to react specifically to the agents.

Zusammenfassung

Mit einer früher beschriebenen Methode zur Sensibilitätstestung (3H-Thymidineinbau, Flüssigkeitsscintillationsmessung) haben wir 30 menschliche Adenocarcinome (10 Rectum-Sigma-Carcinome, 10 Magen-Carcinome, 30 Mamma-Carcinome) gegenüber Trenimon®, Methotrexat® und Natulan® getestet und statistisch ausgewertet. Die in unserer früheren Untersuchung vermutete Individualität der Tumoren konnte bestätigt werden.

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Literatur

  1. Volm, M., Kaufmann, M., Hinderer, H., Goerttler, Kl.: Klin. Wschr.48, 374–376 (1970).

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  2. Kaufmann, M., Volm, M., Goerttler, Kl.: Klin. Wschr.49, 219–223 (1971).

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Authors and Affiliations

  1. Deutsches Krebsforschungszentrum Heidelberg, Institut für Experimentelle Pathologie, Germany

    J. Mattern, M. Kaufmann, M. Volm, U. Schütze, K. Wayss, Kl. Goerttler & C. Tasca

  2. Chirurgische Universitätsklinik Heidelberg, Germany

    U. Schütze

Authors
  1. J. Mattern
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  2. M. Kaufmann
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  3. M. Volm
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  4. U. Schütze
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  5. K. Wayss
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  6. Kl. Goerttler
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  7. C. Tasca
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Additional information

Mit Ausnahme des Erstgenannten ist die Reihenfolge der Autoren streng zufällig.

Stipendiat der Alexander von Humboldt-Stiftung.

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Mattern, J., Kaufmann, M., Volm, M. et al. Zur Sensibilitätstestung maligner menschlicher Tumoren gegenüber Cytostatica. II. Klin Wochenschr 50, 196–198 (1972). https://doi.org/10.1007/BF01487143

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  • DOI: https://doi.org/10.1007/BF01487143

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