Summary
General aspects of glioblastomas are considered such as preoperative diagnosis, stereotactic punctures for tissue samples, location and tumour size, interference with CSF circulation. The operative risk and different approaches to treatment are discussed, and the results are compared. The described combined treatment of operative, local cytostatic, and irradiation therapy appears promising, with 22% of patients alive, and a maximum survival time of 5 1/2 years. Attention is drawn to proper information of the patient and his family regarding the disease and possible outcome.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Blomm, H. J. G., Peckham, M. J., Richardson, A. E., Glioblastoma multiforme: a controlled trial to assess the value of specific active immunotherapy in patients treated by radical surgery and radiotherapy. Brit. J. Cancer27 (1973), 253–267.
Diemath, H. E., Glioblastomerkrankung und Lebensalter. Zbl. für Chir.84 (1959), 1998–2001.
—, Zum Verlauf der Glioblastomerkrankung. Neurochirurgia3 (1960), 45–59.
Garfield, J., Dayan, A. D., Postoperative intracavitary chemotherapy of malignant gliomas: A preliminary study using methotrexate. J. Neurosurg.39 (1973), 315–322.
Heppner, F., Über lokale und allgemeine Anwendung von Cystostatica bei malignen Gliomen. Acta Neurochir. (Wien) Suppl. VI. Wien: Springer. 1959.
—, Diemath, H. E., Über die lokale Applikation von cystostatischen Substanzen im Gehirn. Wien. med. Wschr.111 (1961), 725–726.
Vogt, U., Neurologische Diagnose und Verlauf des Glioblastoms. Dtsch. med. Wschr.79 (1972), 717–722.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Diemath, H.E. Operative indications in glioblastoma. Acta neurochir 42, 117–121 (1978). https://doi.org/10.1007/BF01406638
Issue Date:
DOI: https://doi.org/10.1007/BF01406638